The Mwali Biosphere Reserve encompasses the entire land and marine territory of Moheli, the smallest of the islands of the Union of the Comoros, which is located in the Mozambique Channel ecoregion.
Its location in this area gives it a high level of biological diversity and endemicity, with a continental shelf extending down to the 100m isobath, in the intertropical marine biogeographic region of the south-west Indian Ocean.
